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Amazon RDS (Relational Database Service) is a managed service that makes it easy to set up, operate, and scale relational databases in the cloud. It handles many of the administrative tasks associated with databases, such as backups, software patching, and hardware maintenance, so you can focus on your applications. RDS supports several popular database engines, like MySQL, PostgreSQL, Oracle, and SQL Server, allowing you to choose the one that best fits your needs. Essentially, it lets you easily create and manage databases in AWS without the complexities of managing the underlying infrastructure.